GRADE approach for determining certainty of evidence on how patients value outcomes – Patient Outcome Importance Workshop II


Workshop session 8: Saturday, 11:00-12:30

Workshop category: 

  • Methods for conducting syntheses (including different evidence, searching and information retrieval, statistics, assessing methodological quality)


Date and Location


Saturday 16 September 2017 - 11:00 to 12:30


Contact persons and facilitators

Contact person:


Yuan Zhang
Hector Pardo-Hernandez
Juan Yepes-Nuñez
Gordon Guyatt
Holger Schunemann
Target audience

Target audience: 

Guideline and systematic review developers, methodologists, or anyone interested in discussing this topic.

Level of difficulty: 

Type of workshop

Type of workshop : 



Objectives: To discuss, from the GRADE perspective, how to assess quality of evidence regarding the relative importance or value that patients place on outcomes relevant to systematic reviews or clinical practice guidelines. Using examples from the literature, to assess risk of bias within and across studies that address the importance or value patients place on relevant outcomes. To discuss applicability of this approach for systematic review authors and guideline panellists.

Description: Attendance of this workshop is contingent on attendance to the 'Integrating patient outcome importance in guideline development: Patient Outcome Importance Workshop I'.

To date, no formal GRADE guidance exists regarding how to assess quality of evidence about the relative importance or value patients place on outcomes of alternative management strategies. In this workshop we will discuss a GRADE approach to rate the certainty of this evidence and to present results and certainty in evidence profiles.

This workshop will consist of short presentations where we will introduce the basic concepts and measurements of outcome importance and how this type of evidence can be integrated into clinical guidelines. We will also discuss the proposed GRADE approach using illustrative examples. There will also be small group work where participants will have the opportunity to carry on quality of evidence assessment using a prepared example. Facilitators will answer questions and collect feedback.