Evaluating the clinical credibility and implementability of clinical practice guideline recommendations using the AGREE-REX tool


Workshop session 6: Thursday, 16:00-17:30

Workshop category: 

  • Enhancing the implementability of evidence tools


Date and Location


Thursday 14 September 2017 - 16:00 to 17:30


Contact persons and facilitators

Contact person:


Melissa Brouwers
Ivan D. Florez
Karen Spithoff


Kerkvliet K1
1 McMaster University, Canada
Target audience

Target audience: 

Clinical practice guideline developers and guideline users/implementers

Level of difficulty: 

Type of workshop

Type of workshop : 



Objectives: To learn how to apply the AGREE-REX tool to assess the clinical credibility and implementability of clinical practice guideline recommendations.
To learn how the principles outlined by the AGREE-REX can be used to optimise the development and reporting of clinically credible and implementable guideline recommendations.

Description: The AGREE II is a widely used tool to assess the overall methodological quality of clinical practice guidelines; however, guidelines with high overall methodological quality are not guaranteed to have trustworthy or applicable recommendations. The AGREE-REX has been recently developed as a complement to the AGREE II for assessing the clinical credibility and implementability of guideline recommendations. Workshop participants will learn about when it is appropriate to use the AGREE-REX versus the AGREE II or other evaluation tools and will receive hands-on training by applying the AGREE-REX to a clinical practice guideline. Participants will have a chance to provide feedback about the tool and its application. A discussion will be held about how the AGREE-REX can be used by guideline developers to improve the trustworthiness and implementability of their own guideline recommendations and by guideline users to identify appropriate guidelines/recommendations for implementation or adaptation in their own context.